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Rainbow trout testis development
Phylogenetically conserved expression patterns in spermatogenesis and testis-specific genes of the male rainbow trout are shown by transcriptome analysis, identifying new pathways involved during spermatogonia self-renewal, meiosis and gamete differentiation.
BMC Genomics 2009, 10:546

Social network for Darwin's friends
Scratchpads, a new social networking tool for natural history researchers and enthusiasts, links information from disparate sources, encourages data sharing, and promotes the ultimate goal of describing and synthesising all facets of the diversity of life.
BMC Bioinformatics 2009, 10:S6

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 Welcome to Genome Biology
  Biology for the post-genomic era.

Software    
Crossbow
Langmead B, Schatz MC, Lin J, Pop M, Salzberg SL / 20 November 2009

Novel software utilizing cloud computing technology to cost-effectively align and map SNPs from a human genome in three hours.

Research    
Assortative mating in Latino populations
Risch N, Choudhry S, Via M, Basu A, Sebro R, Eng C, Beckman K, Thyne S, Chapela R, Rodriguez-Santana JR, et al. / 20 November 2009

Examination of ancestry-informative genetic markers shows that Puerto Rican and Mexican populations have shown strong assortative mating that continues to this day.

Protein family review   
The SR protein family
Shepard PJ, Hertel KJ / 27 October 2009

The SR proteins are not only involved in pre-mRNA splicing but in mRNA export and the initiation of translation.

Minireview   
Comparing cellular proteomes by mass spectrometry
Fröhlich F, Walther TC / 28 October 2009

Mass spectrometry and cryo-electron tomography together can enable absolute protein abundance to be determined.

Method    
COMIT
Kural D, Ding Y, Wu J, Korpi A, Chuang JH / 20 November 2009

COMIT is presented; an algorithm for detecting functional non-coding motifs in coding regions, separating nucleotide and amino acid effects.


Sequencing of the potato late blight pathogen Phytophthora infestans provides insight into the structure and evolution of its genome.

Research    
FOXA1 and FOXA3 binding patterns
Motallebipour M, Ameur A, Reddy Bysani MS, Patra K, Wallerman O, Mangion J, Barker MA, McKernan KJ, Komorowski J, Wadelius C / 17 November 2009

FOXA1 and FOXA3 binding patterns in HepG2 cells, together with their possible molecular interactions with FOXA2 and each other, are revealed by ChIP-seq.

The complete issue of Genome Biology Volume 10 Issue 10 is now available.

Comment   
Petsko GA / 04 November 2009
Software    
Wu C, Orozco C, Boyer J, Leglise M, Goodale J, Batalov S, Hodge CL, Haase J, Janes J, Huss JW, et al. / 17 November 2009
Meeting report   
Byun R, Becskei A / 19 November 2009
Research    
Wang S, Zhang L, Meyer E, Matz MV / 09 November 2009
Protein family review   
Rajasekharan S, Kennedy TE / 29 September 2009
Research    
Marques AC, Ponting CP / 06 November 2009
Meeting report   
Munson M, Bolon DN / 27 October 2009
Research    
Pankla R, Buddhisa S, Berry M, Blankenship DM, Bancroft GJ, Banchereau J, Lertmemongkolchai G, Chaussabel D / 10 November 2009
Review    
Gabaldón T / 30 October 2008

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