Biology for the post-genomic era

Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.


  • Louisa Flintoft PhD, Genome Biology


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    Transcriptome assembly evaluation

    RSEM-EVAL, a novel model-based score, evaluates the with accuracy de novo transcriptome assembly of species lacking a sequenced genome

    Genome Biology 2014, 15:553
  • Image-guided genomics

    Roel Verhaak and Kosuke Yoshihara discuss how using imaging data can assist novel cancer drivers prediction

    Genome Biology 2014, 15:563
  • Missing bird genes

    Birds lack numerous protein coding genes which are present in the majority of other vertebrate lineages in conserved syntenic clusters

    Genome Biology 2014, 15:565
  • Surfing data waves

    John Novembre and colleagues reflect on the recent ASHG 2014 meeting in San Diego.

    Genome Biology 2014, 15:562
  • kPAL: quality assessment

    The kPAL package assesses the quality of sequencing datasets, detects technical artifacts and differences in library preparation protocols

    Genome Biology 2014, 15:555
  • Gut microbiome genetics

    Analysis of a mouse cross reveals host genes that alter the gut microbiome in addition to dietary factors that do

    Genome Biology 2014, 15:552
  • Ovarian cancer driver

    A combined analysis of immunohistochemical and genomic data for ovarian cancer reveals that PTEN loss is a common and prognostic driver event

    Genome Biology 2014, 15:526
  • Crested ibis genome

    Comparisons of the genomes of the endangered crested ibis and the little egret reveals the effects near-extinction has on genomes

    Genome Biology 2014, 15:557
  • Biased gene conversion

    Evidence from 48 avian genomes suggests that GC-biased gene conversion is more effective in large populations with shorter generation time

    Genome Biology 2014, 15:549
  • Population size proxies

    Kr/Kc correlates with body mass, whereas dN/dS is negatively correlated, suggesting that dN/dS is a poor measure for estimating selection

    Genome Biology 2014, 15:542
  • Avian endogenous viruses

    A survey of 48 sequenced bird genomes reveals a relatively small number of endogenous viral elements

    Genome Biology 2014, 15:539

Featured review

The indoor microbiomeThe indoor microbiome

Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study.



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