Biology for the post-genomic era
Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.
- Clare Garvey PhD, Genome Biology
Deletion mutants for all 4,772 non-essential yeast genes, representing the long-awaited prototrophic collection, are profiled in 28 metabolic environments
Transcription of ANGPTL4 is controlled by HIF1 and PPAR signaling physically repositioning two response elements
A genome-wide analysis of H3.3 in Arabidopsis shows that H3.3 is localized in gene bodies and promoters, and is H2A.Z-independent
A method for identifying regulatory hotspots in eQTL data that reduces the problem of detecting spurious hotspots
Have we underestimated the number of human miRNAs? Evidence for over 1,000 novel candidates is supported by a new capture method
An epigenetic analysis of depression in 50 monozygotic twin pairs identifies significant hypermethylation associated with the coding region of ZBTB20
Analysis of the genomes and exomes of diffuse- and intestinal-type gastric cancers reveals new somatic variants, including a novel fusion gene
A survey of 17 human tissues identifies tissue-specific methylation patterns
A Research Highlight from Robin Buell and John Hamilton elegantly discusses how the loblolly pine megagenome was sequenced
Jacob Hanna and Asaf Zviran ask: What makes somatic cells convert to stem cells? How much is due to dumb luck?
Characterizing Runx2 genome-wide occupancy shows that Runx2 functions at promoter and non-promoter regions to control osteoblastogenesis
Featured free review
Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study.
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Free webinar on plant genomics:
Breeding opportunities out of challenges, broadcast live 18th April 2013 sponsored by Affymetrix. A free to view panel discussion between Clare Garvey, Editor – Genome Biology, BioMed Central, Etienne Paux, INRA and Doreen Ware, USDA ARS, Adjunct Associate Professor, Cold Spring Harbor Laboratory.
From the blog
- 28 February 2014
- Methylating much?