Biology for the post-genomic era
Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.
Articles
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Genome Biology 2012, 13:139DNA-protein interactions
Mendenhall and Bernstein highlight ChIP-exo, which is an elegant, genome-wide approach to define the precise DNA sequences bound by transcription factors
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Genome Biology 2012, 13:140Whack-an-E. coli
Nathalie Balaban and colleagues highlight a landmark study of antibiotic resistance evolutionary trajectories, which is centered on a morbidostat
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Genome Biology 2012, 13:R3Genome triplication in eudicots
An investigation of when the gamma polyploidization event occurred in relation to speciation events in angiosperm history
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Genome Biology 2012, 13:R2Ashkenazi Jewish genetics
A population-specific genetic signature, derived from a large genotyping study, helps explain why some diseases are overrepresented in the Ashkenazi population
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Genome Biology 2012, 13:237Complex genetic disorders
Complex disorders such as diabetes and schizophrenia are really groups of many distinct genetic disorders caused by rare, recent deleterious mutations
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Genome Biology 2012, 13:R1Ethiopian highland genetics
The genetics of hypoxia selection in an Ethiopian high-altitude population are distinct from Andean and Tibetan genotypes, suggestive of convergent evolution
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Genome Biology 2011, 12:R127Meningococcal fitness screen
A global screen of mutant fitness in Neisseria meningitidis was used to construct a genome-scale metabolic network
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Genome Biology 2011, 12:R126miRNAs and isomiRs
IsomiRs act cooperatively with canonical miRNAs to regulate gene expression
Latest issue
The complete issue of Genome Biology Volume 12 Issue 12 is now available.
Genome Biology podcast
To coincide with September's special issue, we talk with Jim Lupski, Jay Shendure, Elaine Mardis and Joris Veltman about the challenges of identifying disease genes using exome sequencing and whole genome sequencing.
Download MP3 file (Size: 35.8MB)
Featured free review
Dosage compensation and the global re-balancing of aneuploid genomes
The dosage-compensation systems that equalize X-chromosome expression between sexes exemplify the intricacies of compensating for differences in gene copy number.
From the blog
- 16 January 2012
- Genome Biology special issue on epigenomics
- 21 December 2011
- Genome Biology publishes MiSeq data
Twitter updates
- The Balaban lab call for E. coli-whacking, as they highlight a new strategy for studying antibiotic resistance http://t.co/nQwfxwUy about 12 hours ago
- @DiscoverMag Razib Khan blogs about our Ethiopian high altitude genetics article, suggests future research directions http://t.co/viziuiwn about 12 hours ago
- Research Highlight: Eric Mendenhall & Brad Bernstein on ChIP-exo, the Pugh lab's high res ChIP-seq method http://t.co/Uj0yS8HO #genomics about 16 hours ago
Article series
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The tammar wallaby genome and transcriptome
Published: 10 August 2011
Last updated: 11 January 2012
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