Biology for the post-genomic era

Genome Biology publishes research articles, new methods and software tools, in addition to reviews and opinions, from the full spectrum of biology, including molecular, cellular, organism or population biology studied from a genomic perspective, as well as sequence analysis, bioinformatics, proteomics, comparative biology and evolution.


  • Clare Garvey PhD, Genome Biology


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  • Prototrophic deletion collection

    Deletion mutants for all 4,772 non-essential yeast genes, representing the long-awaited prototrophic collection, are profiled in 28 metabolic environments

    Genome Biology 2014, 15:R64
  • Response element conformation

    Transcription of ANGPTL4 is controlled by HIF1 and PPAR signaling physically repositioning two response elements

    Genome Biology 2014, 15:R63
  • Arabidopsis H3.3 distribution

    A genome-wide analysis of H3.3 in Arabidopsis shows that H3.3 is localized in gene bodies and promoters, and is H2A.Z-independent

    Genome Biology 2014, 15:R62
  • NICE

    A method for identifying regulatory hotspots in eQTL data that reduces the problem of detecting spurious hotspots

    Genome Biology 2014, 15:R61
  • Novel human miRNAs

    Have we underestimated the number of human miRNAs? Evidence for over 1,000 novel candidates is supported by a new capture method

    Genome Biology 2014, 15:R57
  • Epigenetics of depression

    An epigenetic analysis of depression in 50 monozygotic twin pairs identifies significant hypermethylation associated with the coding region of ZBTB20

    Genome Biology 2014, 15:R56
  • Gastric cancer genomics

    Analysis of the genomes and exomes of diffuse- and intestinal-type gastric cancers reveals new somatic variants, including a novel fusion gene

    Genome Biology 2014, 15:R55
  • Tissue-specific methylation

    A survey of 17 human tissues identifies tissue-specific methylation patterns

    Genome Biology 2014, 15:R54
  • Pine research highlight

    A Research Highlight from Robin Buell and John Hamilton elegantly discusses how the loblolly pine megagenome was sequenced

    Genome Biology 2014, 15:111
  • Stochastic cell reprogramming

    Jacob Hanna and Asaf Zviran ask: What makes somatic cells convert to stem cells? How much is due to dumb luck?

    Genome Biology 2014, 15:109
  • Osteoblastogenesis regulation

    Characterizing Runx2 genome-wide occupancy shows that Runx2 functions at promoter and non-promoter regions to control osteoblastogenesis

    Genome Biology 2014, 15:R52

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The indoor microbiomeThe indoor microbiome

Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study.



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Genome Biology Volume 15 Issue 3

The complete issue of Genome Biology Volume 15 Issue 3 is now available.

Free webinar on plant genomics:

Breeding opportunities out of challenges, broadcast live 18th April 2013 sponsored by Affymetrix. A free to view panel discussion between Clare Garvey, Editor – Genome Biology, BioMed Central, Etienne Paux, INRA and Doreen Ware, USDA ARS, Adjunct Associate Professor, Cold Spring Harbor Laboratory.

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ISSN: 1465-6906