Can the selection by aminoacyl-tRNA synthetases for the correct tRNA substrate happen during binding? The results of equilibrium experiments suggest that it can.

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How aminoacyl-tRNA synthetase recognizes tRNA


Can the selection by aminoacyl-tRNA synthetases for the correct tRNA substrate happen during binding? The results of equilibrium experiments suggest that it can.

tRNA discrimination at the binding step by a class II aminoacyl-tRNA synthetase.

ML Bovee, W Yan, BS Sproat and CS Francklyn

Biochemistry 1999, 38: 13725-13735

[Read the abstract on PubMed]

Subject areas: Biochemistry and structural biology, Molecular biology

Reported by: Rachel Brem

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