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Paper report

How is the human signal peptide recognized?

Rachel Brem

  • Correspondence: Rachel Brem

Author Affiliations

Genome Biology 2000, 1:reports020  doi:10.1186/gb-2000-1-1-reports020

Published: 27 April 2000


The crystal structure of human SRP54M from the signal recognition particle (SRP) reveals a homodimer interaction, which may be a model for the way signal sequences on nascent proteins recognize and activate the SRP.