Molecular mechanisms of spindle function
Medical Sciences, Indiana University, Bloomington, IN 47405, USA
Genome Biology 2000, 1:reviews101-reviews101.4 doi:10.1186/gb-2000-1-1-reviews101Published: 27 April 2000
The key molecules involved in regulating the assembly and function of the mitotic spindle are shared by evolutionarily divergent species. Studies in different model systems are leading to convergent conclusions about the central role of microtubule nucleation and dynamics and of kinesin-related motor proteins in spindle function.