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For B cells, less is more

William Wells

Genome Biology 2000, 1:spotlight-20000531-01  doi:10.1186/gb-spotlight-20000531-01

Published: 31 May 2000

The transcription factor PU.1 is needed for the formation of both macrophages and B cells. High PU.1 makes macrophages, whereas low PU.1 makes B cells.