Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Research news

Stem cells branch out

William Wells

Author Affiliations

Genome Biology 2000, 1:spotlight-20000607-02  doi:10.1186/gb-spotlight-20000607-02


The electronic version of this article is the complete one and can be found online at:


Published:7 June 2000

© 2000 BioMed Central Ltd

Research news

Differentiation of embryonic stem (ES) cells, which are originally totipotent, puts increasing restrictions on the final fates that a cell can achieve. This simple idea was upset last year when neural stem cells were shown to produce blood cells in irradiated adult mice. In the 2 June issue of Science, Clarke et al. show that neural stem cells injected into embryos can generate a wide variety of tissues including cells in the central nervous system, heart, liver, and intestine (Science 2000, 288:1660-1663). This raises the possibility of using similar stem cells for human therapy, in place of the ethically questionable use of human ES cells.

References

  1. PubMed Abstract | Publisher Full Text OpenURL

  2. [http://www.sciencemag.org/] webcite

    Science magazine