Table 2

Host and pathogen DNA array studies

Cell type
Pathogen
Array
Genes
Array type and support
Experiment
Reference

Human foreskin fibroblasts
Human cytomegalovirus
Pathogen
207 genes
Oligonucleotides on glass slides
Virus gene expression during lytic replication
[5]
Human B-cell*
Human herpesvirus 8
Pathogen
120 genes
PCR products on nylon
Virus gene expression during latent and lytic replication
||
Human T-cell
Human immuno-deficiency virus type 1
Host
1,500 genes
PCR products on glass slides
Host gene expression during 72 hours of virus infection
[7]
Normal human keratinocytes
Human papillomavirus type 31
Host
7,075 genes
PCR products on glass slides
Host gene expression following transfection of the viral genome
[8]
Human foreskin fibroblasts
Human cytomegalovirus
Host
6,600 genes
Affymetrix microarrays
Host gene expression during 24 hours of virus infection
[6]
Human colorectal and colon§ epithelial cells
Salmonella dublin
Host
4,300 genes
PCR products on nylon
Host gene expression during 20 hours of bacterial infection
[10]
Human monocytes
Listeria monocytogenes
Host
6,800 genes, 18,367 genes, 588 genes
Affymetrix microarrays, PCR products on nylon
Host gene expression during 2 hours of bacterial infection
[9]

*Primary effusion lymphoma cell line BC-3; T-cell lymphoma cell line CEMCCRF; HT-29 cells; §T84 cells; THP- I cells. ||R.G. Jenner, et al., unpublished observations.

Kellam Genome Biology 2000 1:reviews1009.1   doi:10.1186/gb-2000-1-2-reviews1009