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Review

A comparison of programmed cell death between species

Jan N Tittel1 and Hermann Steller12*

Author Affiliations

1 Howard Hughes Medical Institute, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA

2 The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA

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Genome Biology 2000, 1:reviews0003-reviews0003.6  doi:10.1186/gb-2000-1-3-reviews0003

Published: 13 September 2000

Abstract

Key components of the programmed cell death pathway are conserved between Caenorhabditis elegans, Drosophila melanogaster and humans. The search for additional homologs has been facilitated by the availability of the entire genomic sequence for each of these organisms.