A conserved mechanism for post-transcriptional gene silencing?
Department of Biology, Syracuse University, Syracuse, NY 13244, USA
Genome Biology 2000, 1:reviews1018-reviews1018.4 doi:10.1186/gb-2000-1-3-reviews1018Published: 13 September 2000
Proteins with homology to RNA-directed RNA polymerases function in post-transcriptional gene silencing: in quelling in the fungus Neurospora crassa, RNAi in the nematode Caenorhabditis elegans, and co-suppression in the mustard plant Arabidopsis thaliana. These findings are consistent with a conserved mechanism operating in these diverse species.