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Does massively parallel transcriptome analysis signify the end of cancer histopathology as we know it?

Samuel AJR Aparicio*, Carlos Caldas and Bruce Ponder

Author Affiliations

Department of Oncology, University of Cambridge, Wellcome Trust/MRC Building, Addenbrookes Hospital, Cambridge CB2 2XY,UK

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Genome Biology 2000, 1:reviews1021-reviews1021.3  doi:10.1186/gb-2000-1-3-reviews1021

Published: 15 September 2000

Abstract

Transcriptional analysis of all the genes expressed by breast tumors has provided the first steps towards defining a molecular signature for the disease, and might ultimately make conventional diagnostic techniques obsolete.