Table 1

Phyletic distributions of the six families of UNGs

Species/family
UNG*
AUDG*
MUG
SsUDG* DRUDG*



+ UDGX*


Bacteria




     Escherichia coli
1

1 (MUG)

     Haemophilus influenzae
1
1


     Neisseria meningitidis
1
1
1 (UDGX)

     Rickettsia prowazekii

1


     Campylobacter jejuni
1
1
1 (UDGX)

     Helicobacter pylori
1
1


     Bacillus subtilis
1



     Mycoplasma genitalium
1



     Mycoplasma pneumoniae
1



     Ureaplasma urealyticum
1



     Deinococcus radiodurans
1
1
1 (MUG)
1
     Mycobacterium tuberculosis 1

1


     Streptomyces coelicolor
1
2


     Synechocystis sp.

1


     Chlamydia trachomatis
1



     Chlamydophila pneumoniae 1




     Treponema pallidum

1


     Borrelia burgdorferi
1
1(d)


     Aquifex aeolicus

1


     Thermotoga maritima

1


Archaea




     Aeropyrum pernix

1


     Archaeoglobus fulgidus

1


     Pyrococcus horikoshii

1


     Methanobacterium




          thermoautotrophicum




     Methanococcus jannaschii




Eukaryota




     Saccharomyces cerevisiae
1

(r)

     Schizosaccharomyces pombe1


1(MUG)

     Caenorhabditis elegans
1



     Drosophila melanogaster
(?)§

1(MUG)
1
     Homo sapiens
1

1(MUG)
1
Large DNA viruses




     Poxviruses
1



     Herpesviruses
1



     Bacteriophages SPO1

1



*The number of detected representatives of each family is indicated for each species. Note that duplication is uncharacteristic of the UNGs. (d) indicates a possibly disrupted version in which the amino-terminal conserved motifs are not detectable; (r) indicates an apparent recent loss in S. cerevisiae, as the gene is retained in the related yeast Candida albicans; §(?) indicates the unusual lack of a detectable UNG in both the genome and EST sequences.

Aravind and Koonin Genome Biology 2000 1:research0007.1   doi:10.1186/gb-2000-1-4-research0007