Genome Biology
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ReviewAn overview of the potassium channel familyChristopher Miller  HHMI and Department of Biochemistry, Brandeis University, Waltham, MA 02454, USA  author email corresponding author email
Genome Biology 2000,
1:reviews0004.1-0004.5doi:10.1186/gb-2000-1-4-reviews0004
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| Published: |
13 October 2000 |
Subject areas: Cell biology, Physiology Abstract
Potassium channels, tetrameric integral membrane proteins that form aqueous pores through which K+ can flow, are found in virtually all organisms; the genomes of humans, Drosophila, and Caenorhabditis elegans contain 30-100 K+ channel genes each. The structure of a bacterial K+ channel, sequence comparisons with other channels and electrophysiological measurements have enabled conclusions about the mechanism of gating and ion flow to be drawn for many other channels. | 
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