Genome Biology

official impact factor 6.89

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From biological clock to biological rhythms

Paul E Hardin

Author Affiliations

Department of Biology and Biochemistry, University of Houston, Houston, TX 77204-5513, USA

Genome Biology 2000, 1:reviews1023-reviews1023.5 doi:10.1186/gb-2000-1-4-reviews1023

Published: 10 October 2000

Abstract

The genetic and molecular analysis of circadian timekeeping mechanisms has accelerated as a result of the increasing volume of genomic markers and nucleotide sequence information. Completion of whole genome sequences and the use of differential gene expression technology will hasten the discovery of the clock output pathways that control diverse rhythmic phenomena.