Genome Biology
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MinireviewSecret sharers in the immune system: a novel RNA editing activity links switch recombination and somatic hypermutationNancy Maizels  Departments of Immunology and Biochemistry, University of Washington Medical School, 1959 NE Pacific Street, Seattle, WA 98195-7650, USA  author email corresponding author email
Genome Biology 2000,
1:reviews1025.1-1025.3doi:10.1186/gb-2000-1-4-reviews1025
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| Published: |
13 October 2000 |
Subject areas: Immunology, Molecular biology, Genetics, Medicine Abstract
A new mechanism for regulation in the immune system has been identified: a cytidine deaminase is critical for both class switch recombination and somatic hypermutation, revealing an unanticipated link between these two processes. | 
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