Table 1

Phyletic distributions of the six families of UNGs

Species/family

UNG^*

AUDG^*

MUG

SsUDG^* DRUDG^*

+ UDGX^*

Bacteria

Escherichia coli

1

1 (MUG)

Haemophilus influenzae

1

1

Neisseria meningitidis

1

1

1 (UDGX)

Rickettsia prowazekii

1

Campylobacter jejuni

1

1

1 (UDGX)

Helicobacter pylori

1

1

Bacillus subtilis

1

Mycoplasma genitalium

1

Mycoplasma pneumoniae

1

Ureaplasma urealyticum

1

Deinococcus radiodurans

1

1

1 (MUG)

1

Mycobacterium tuberculosis 1

1

Streptomyces coelicolor

1

2

Synechocystis sp.

1

Chlamydia trachomatis

1

Chlamydophila pneumoniae 1

Treponema pallidum

1

Borrelia burgdorferi

1

1(d)^†

Aquifex aeolicus

1

Thermotoga maritima

1

Archaea

Aeropyrum pernix

1

Archaeoglobus fulgidus

1

Pyrococcus horikoshii

1

Methanobacterium

thermoautotrophicum

Methanococcus jannaschii

Eukaryota

Saccharomyces cerevisiae

1

(r)^‡

Schizosaccharomyces pombe1

1(MUG)

Caenorhabditis elegans

1

Drosophila melanogaster

(?)^§

1(MUG)

1

Homo sapiens

1

1(MUG)

1

Large DNA viruses

Poxviruses

1

Herpesviruses

1

Bacteriophages SPO1

1

^*The number of detected representatives of each family is indicated for each species. Note that duplication is uncharacteristic of the UNGs. ^†(d) indicates a possibly disrupted version in which the amino-terminal conserved motifs are not detectable; ^‡(r) indicates an apparent recent loss in S. cerevisiae, as the gene is retained in the related yeast Candida albicans; ^§(?) indicates the unusual lack of a detectable UNG in both the genome and EST sequences.

Aravind and Koonin Genome Biology 2000 1:research0007.1   doi:10.1186/gb-2000-1-4-research0007