Expression profiling in reference bacteria: dreams and reality
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* Corresponding author: Antoine Danchin adanchin@hkucc.hku.hk
Pasteur Research Centre, Hong Kong University, 8 Sassoon Road, Pokfulam, Hong Kong
Genome Biology 2000, 1:reviews1024-reviews1024.5 doi:10.1186/gb-2000-1-4-reviews1024
Published: 10 October 2000Abstract
Profiling of gene expression in bacteria is now being used to uncover unknown genes expressed in particular genetic backgrounds or environmental conditions. Obtaining the best possible information from the expected avalanche of such experiments will require standardization of both experimental approach and statistical analysis. The first such experiments reveal challenges, pitfalls and reasonable solutions.