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Expression profiling in reference bacteria: dreams and reality

Antoine Danchin email and Agnieszka Sekowska

Pasteur Research Centre, Hong Kong University, 8 Sassoon Road, Pokfulam, Hong Kong

author email corresponding author email

Genome Biology 2000, 1:reviews1024.1-1024.5doi:10.1186/gb-2000-1-4-reviews1024

Published: 10 October 2000

Subject areas: Microbiology and parasitology, Genome studies, Bioinformatics, Methods

Abstract

Profiling of gene expression in bacteria is now being used to uncover unknown genes expressed in particular genetic backgrounds or environmental conditions. Obtaining the best possible information from the expected avalanche of such experiments will require standardization of both experimental approach and statistical analysis. The first such experiments reveal challenges, pitfalls and reasonable solutions.


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