Figure 1.

The F-box consensus sequence. The consensus was derived from the alignment of 234 sequences used to create the Pfam F-box profile [30]; the single-letter amino-acid code is used. Bold and underlined capital letters signify residues found in over 40% of the F-box sequences; bold, non-underlined, capital letters signify residues found in 20-40% of the F-boxes; bold lower case letters indicate residues found in 15-19% of the F-boxes; and non-bold lower case letters indicate residues found in 10-14% of the F-boxes. A minority of F-boxes contain small insertions in the alignment after positions 11 or 24, or small (1-3 residue gaps) at various locations.