Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Research news

This amoeba is a cheater

William Wells

Genome Biology 2000, 1:spotlight-20001228-01  doi:10.1186/gb-spotlight-20001228-01

The electronic version of this article is the complete one and can be found online at:


Published:28 December 2000

© 2000 BioMed Central Ltd

Research news

Dictyostelium discoideum are usually haploid, asexually dividing, unicellular amoebae, but when starved they aggregate to form a slug that then differentiates to form a sterile stalk supporting viable spore cells. In the 21/28 December Nature Strassmann et al. find that Dictyostelium of different genotypes can combine to form a chimeric fruiting body, and that half of the chimeras contain cells that cheat to maximize their contribution to the spore cell compartment (Nature 2000, 408:965-967). The more effective cheaters are not biased to form more spore cells in all situations. When these cheaters are induced to form slugs and fruiting bodies of a single genotype, they do not make greater numbers of spores versus stalk cells, suggesting that in the chimeras a special cheating process is being activated. This makes Dictyostelium an excellent model system for studies of altruism and cheating, but may complicate developmental studies, as many between-cell signaling events may involve deception and manipulation.

References

  1. [http://www.nature.com/nature/] webcite

    Nature

  2. Dictyostelium amoebae lacking an F-box protein form spores rather than stalk in chimeras with wild type.

    PubMed Abstract | Publisher Full Text | PubMed Central Full Text OpenURL