Genome Biology Volume 2 Issue 1 |
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OpinionPolymorphism in regulatory gene sequencesN A Mitchison  Department of Immunology, Windeyer Institute of Medical Science, University College London Medical School, Cleveland Street, London W1P 6DB, UK author email corresponding author email
Genome Biology 2000,
2:comment2001.1-2001.6doi:10.1186/gb-2000-2-1-comment2001
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| Published: |
20 December 2000 |
Subject areas: Immunology, Molecular biology, Medicine, Genome studies, Evolution Abstract
The extensive polymorphism revealed in non-coding gene-regulatory sequences, particularly in the immune system, suggests that this type of genetic variation is functionally and evolutionarily far more important than has been suspected, and provides a lead to new therapeutic strategies. |