Log on / register
BioMed Central home | Journals A-Z | Feedback | Support | My details
.comment
 |  |  |  |  | 


Opinion

Polymorphism in regulatory gene sequences

N A Mitchison email

Department of Immunology, Windeyer Institute of Medical Science, University College London Medical School, Cleveland Street, London W1P 6DB, UK

author email corresponding author email

Genome Biology 2000, 2:comment2001.1-2001.6doi:10.1186/gb-2000-2-1-comment2001

Published: 20 December 2000

Subject areas: Immunology, Molecular biology, Medicine, Genome studies, Evolution

Abstract

The extensive polymorphism revealed in non-coding gene-regulatory sequences, particularly in the immune system, suggests that this type of genetic variation is functionally and evolutionarily far more important than has been suspected, and provides a lead to new therapeutic strategies.


© 1999-2009 BioMed Central Ltd unless otherwise stated. Part of Springer Science+Business Media.