Opinion
Polymorphism in regulatory gene sequences
Department of Immunology, Windeyer Institute of Medical Science, University College London Medical School, Cleveland Street, London W1P 6DB, UK
Genome Biology 2000, 2:comment2001-comment2001.6 doi:10.1186/gb-2000-2-1-comment2001
Published: 20 December 2000Abstract
The extensive polymorphism revealed in non-coding gene-regulatory sequences, particularly in the immune system, suggests that this type of genetic variation is functionally and evolutionarily far more important than has been suspected, and provides a lead to new therapeutic strategies.
