Table 5

Simulation results
Scenario
 Average
 Average
 Proportion
 Proportion
 Average

number
 number
 of harvest
 of true
 correlation

in
 in
 genes in
 genes in

true
 estimate
 true
 harvest
3,624 total genes, 36 samples. Relative risk = 2.0 in additive scenarios
p =1
 1.0
 2.4
 0.80
 0.80
 0.86
2 <p < 10
 3.4
 4.8
 0.60
 0.60
 0.91
10 <p <300
 26.2
 6.4
 0.60
 0.19
 0.77
Interaction
 3.4
 2.6
 0.28
 0.21
 0.65
3,624 total genes, 36 samples. Relative risk = 1.0 in additive scenarios
p =1
 1.0
 1.6
 0.24
 0.60
 0.61
2 <p <10
 3.4
 4.6
 0.13
 0.20
 0.58
10 <p <300
 26.2
 3.8
 0.40
 0.21
 0.61
1,622 total genes, 129 samples. Relative risk = 2.0 in additive scenarios
p = 1
 1.00
 1.60
 0.77
 1.00
 0.97
2 <p <10
 2.80
 3.00
 0.93
 1.00
 0.99
10 <p <300
 64.6
 16.6
 0.94
 0.66
 0.91
Interaction
 9.4
 7.6
 0.85
 0.87
 0.86

The value p is the number of genes in the true underlying model.

Hastie et al. Genome Biology 2001 2:research0003.1   doi:10.1186/gb-2001-2-1-research0003