Table 1

Summary of the enzyme activities of the nitrilase superfamily

Nitrilase branch

Nitrilase

Amidase

Reverse amidase

Carbamylase

Protein substrate


R-CN


1 - Nitrilase

Yes

2 - Aliphatic amidase

Yes

3 - Amino-terminal amidase

Yes

Yes

4 - Biotinidase

Yes

Yes

Sometimes

5 -β-Ureidopropionase

Yes

Yes

6 - Carbamylase Yes

Yes

7 - Prokaryote NAD synthetase

Predicted

8 - Eukaryote NAD synthetase

Predicted

9 - Apolipoprotein N-acyltransferase

Yes

Yes

Yes

10 -Nit and Nitfhit

11 -NB11

12 -NB12

Predicted

13 -Nonfused outliers


Pace and Brenner Genome Biology 2001 2:reviews0001.1   doi:10.1186/gb-2001-2-1-reviews0001