Genome Biology

official impact factor 6.89

Open Access

Optimality of the genetic code with respect to protein stability and amino-acid frequencies

Dimitri Gilis*, Serge Massar, Nicolas J Cerf and Marianne Rooman

Genome Biology 2001, 2:research0049-research0049.12 doi:10.1186/gb-2001-2-11-research0049

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BioMed Central: 2 citations

Software   Open Access

An interactive visualization tool to explore the biophysical properties of amino acids and their contribution to substitution matrices

Blazej Bulka, Marie desJardins, Stephen J Freeland BMC Bioinformatics 2006, 7:329 (3 July 2006)

Review   Free Highly Accessed

Statistical tests for differential expression in cDNA microarray experiments

Xiangqin Cui, Gary A Churchill Genome Biology 2003, 4:210 (17 March 2003)

The simplest statistical method for extracting biological information from microarray data is the t test. Analysis of variance (ANOVA) and the mixed ANOVA model are general and powerful approaches for more complex microarray experiments.