Table 2 |
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|
Mouse and human granzymes grouped according to their chromosomal localization |
||
| Chromosomal localization |
Species |
Granzyme(s) |
|
|
||
| The 'tryptase' locus |
||
| 5q11-q12 |
Human |
A and tryptase-2 |
| 13D |
Mouse |
A |
| The 'chymase' locus |
||
| 14q11-q12 |
Human |
B and H |
| 14D |
Mouse |
B,C,D*,E,F and G* |
| The 'Met-ase' locus |
||
| 19p13.3 |
Human |
M |
| 10q21.2 |
Mouse |
M |
|
|
||
|
*Granzymes D and G have not been definitively mapped, but are highly homologous to granzymes E and B, respectively. |
||
|
Trapani Genome Biology 2001 2:reviews3014.1 doi:10.1186/gb-2001-2-12-reviews3014 |
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