Table 2 |
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|
Mouse and human granzymes grouped according to their chromosomal localization |
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|
Chromosomal localization |
Species |
Granzyme(s) |
|
|
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|
The 'tryptase' locus |
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|
5q11-q12 |
Human |
A and tryptase-2 |
|
13D |
Mouse |
A |
|
The 'chymase' locus |
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|
14q11-q12 |
Human |
B and H |
|
14D |
Mouse |
B,C,D*,E,F and G* |
|
The 'Met-ase' locus |
||
|
19p13.3 |
Human |
M |
|
10q21.2 |
Mouse |
M |
|
|
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|
*Granzymes D and G have not been definitively mapped, but are highly homologous to granzymes E and B, respectively. |
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|
Trapani Genome Biology 2001 2:reviews3014.1 doi:10.1186/gb-2001-2-12-reviews3014 |
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