Genome Biology
Volume 2
Issue 2 |
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OpinionThe complexity of simplicityScott N Peterson  and Claire M Fraser The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA  author email corresponding author email
Genome Biology 2001,
2:comment2002.1-2002.8doi:10.1186/gb-2001-2-2-comment2002
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8 February 2001 |
Subject areas: Microbiology and parasitology, Genome studies, Bioinformatics, Model organisms Abstract
What is the minimum number of genes or functions necessary to support cellular life? The concept of a 'minimal genome' has become popular, but is it a useful concept, and if so, what might a minimal genome encode? We argue that the concept may be useful, even though the goal of defining a general minimal genome may never be attained. | 
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