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Functional proteomics: large-scale analysis of protein kinase activity
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Correspondence: David S Lawrence dlawrenc@aecom.yu.edu
Department of Biochemistry, The Albert Einstein College of Medicine, Bronx, NY 10530, USA
Genome Biology 2001, 2:reviews1007-reviews1007.3 doi:10.1186/gb-2001-2-2-reviews1007
Published: 7 February 2001Abstract
Proteome-wide sampling of function can be used to shed light on complex biological systems. Protein microarrays have now been used to investigate the substrate specificities of essentially all the protein kinases encoded by the yeast genome.