Genome Biology

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Hyper-IgM syndrome dissected

Tudor Toma

Genome Biology 2001, 2:spotlight-20010309-01 doi:10.1186/gb-spotlight-20010309-01

Published: 9 March 2001

Mutations in the gene encoding NEMO that prevent the normal functioning of NF-?B, can explain the hyper-IgM syndrome associated with ectodermal dysplasia.