Research news
Chromosome instability in colon cancer
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Correspondence: Kenneth Lee kenlee_fr@yahoo.fr
Genome Biology 2001, 2:spotlight-20010323-03 doi:10.1186/gb-spotlight-20010323-03
Published: 23 March 2001Colon cancer is often associated with mutations in the APC gene and with defects in chromosome segregation. Two studies now show that microtubules need APC for proper attachment when they pull chromosomes apart.