An apology for orthologs - or brave new memes
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Correspondence: Eugene V Koonin koonin@ncbi.nlm.nih.gov
Genome Biology 2001, 2:comment1005-comment1005.2 doi:10.1186/gb-2001-2-4-comment1005
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BioMed Central: 3 citations
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Methodology article
Orthology prediction at scalable resolution by phylogenetic tree analysis René TJM van der Heijden, Berend Snel, Vera van Noort, Martijn A Huynen BMC Bioinformatics 2007, 8:83 (8 March 2007) |
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Deposited research article
Using orthologous and paralogous proteins to identify specificity determining residues Leonid A Mirny, Mikhail S Gelfand Genome Biology 2002, 3:preprint0002-preprint0002.20 (19 February 2002) Functional specificity of proteins is assumed to be conserved among orthologs and to be different among paralogs. We used this assumption to identify the residues that determine specificity of protein-DNA and protein-ligand recognition and present a method to compute the statistical significance of the predictions. |
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Correspondence
Orthologs and paralogs - we need to get it right Roy A Jensen Genome Biology 2001, 2:interactions1002-interactions1002.3 (3 August 2001) A response to Homologuephobia, by Gregory A Petsko, |
