Table 1

Comparison of averaged conserved domain ratios between SMART and Proteome Analysis Database and their relationship to Proteome size

SMART Database

Proteome Analysis Database

Average ratio of genes with CD in organism to total genes with CD in 5 organisms

Sum of predicted genes for all 5 organisms

Product

Average ratio of genes with CD in organism to total genes with CD in 3 organisms

Sum of predicted genes for all 3 organisms

Product

Predicted total Genes in Genome

H. sapiens

0.386

100500

38793

35000

D. melanogaster

0.172

100500

17286

0.454

39500

17933

14100

A. thaliana

0.283

100500

28442

26000

C. elegans

0.158

100500

15879

0.405

39500

15998

19100

S. cerevisiae

0.076

100500

7638

0.141

39500

5569.5

6300

Relationship 3 was used for all conserved domains and the results were averaged for each genome. A comparison between both databases yields very similar results for D. melanogaster and C. elegans. S. cerevisiae data differed between the databases but the differences are centered around the predicted total number of genes. Interestingly, both databases gave a ratio of D. melanogaster and C. elegans that exchanged their predicted total genes.

Malek and Haft Genome Biology 2001 2:preprint0004.1   doi:10.1186/gb-2001-2-5-preprint0004