Figure 2.

Protein sequence alignment of deduced amino-acid sequences of 347 human olfactory receptors. The alignment is color-coded according to the physicochemical properties and degree of conservation of amino-acid residues. The following side-chain-based coloring convention for groups of amino acids was used: Ile, Leu, Met, Val, Phe, Tyr, Ala, Trp (green), Lys, Arg (blue), His (light blue), Asp, Glu (red), Ser, Thr (orange), Pro (purple), Gly (magenta), Cys (yellow), Gln, Asn (grey). Positions with greater than 50% conservation (based on the amino-acid similarity groups shown above and PAM250 matrix) are shown as inverse characters on solid background. At the bottom of the figure, locations of the predicted membrane-spanning domains (TM1-7), intracellular loops (IC1-3) and extracellular loops (EC1-3) are indicated by horizontal bars. Positions of the three pairs of conserved cysteine residues are shown as asterisks. This figure is available as an additional data file in PDF format.

Zozulya et al. Genome Biology 2001 2:research0018.1-research0018.12   doi:10.1186/gb-2001-2-6-research0018