Review
Evolution of mammalian genome organization inferred from comparative gene mapping
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702-1201, USA
Genome Biology 2001, 2:reviews0005-reviews0005.8 doi:10.1186/gb-2001-2-6-reviews0005
Published: 5 June 2001Abstract
Comparative genome analyses, including chromosome painting in over 40 diverse mammalian species, ordered gene maps from several representatives of different mammalian and vertebrate orders, and large-scale sequencing of the human and mouse genomes are beginning to provide insight into the rates and patterns of chromosomal evolution on a whole-genome scale, as well as into the forces that have sculpted the genomes of extant mammalian species.
