Genome Biology

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The origin and early evolution of mitochondria

Michael W Gray*, Gertraud Burger and B Franz Lang

Genome Biology 2001, 2:reviews1018-reviews1018.5 doi:10.1186/gb-2001-2-6-reviews1018

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The origin and early evolution of eukaryotes in the light of phylogenomics

Eugene V Koonin Genome Biology 2010, 11:209 (5 May 2010)

This article is part of a collection on 10th Anniversary...

Comparative genomics and new phylogenies of eukaryote groups suggest a scenario in which the mitochondrial endosymbiosis triggered the origin of eukaryotes.

Research article   Open Access

Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species

Celine A Hayden, Giovanni Bosco BMC Genomics 2008, 9:61 (1 February 2008)

Conserved peptide upstream open reading frames in Drosophila preferentially associate with transcripts encoding methyltransferases and mitochondrial proteins, suggesting that Drosophila could be used to study the role of these upstream sequences in mitochondrial function and disease.

Software   Open Access

E-CAI: a novel server to estimate an expected value of Codon Adaptation Index (eCAI)

Pere Puigbò, Ignacio G Bravo, Santiago Garcia-Vallvé BMC Bioinformatics 2008, 9:65 (29 January 2008)

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What makes a mitochondrion?

Joshua L Heazlewood, A Millar, David A Day, James Whelan Genome Biology 2003, 4:218 (28 May 2003)

Experimental analyses of the proteins found in the mitochondria of yeast, humans and Arabidopsis have confirmed some expectations but given some surprises and some insights into the evolutionary origins of mitochondrial proteins.