Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Research news

Viral protein K5 modulates T-cell costimulation

Tudor Toma

Author affiliations

Citation and License

Genome Biology 2001, 2:spotlight-20010620-01  doi:10.1186/gb-spotlight-20010620-01

Published: 20 June 2001

The expression of the herpesvirus gene K5 in B cells dramatically reduces ICAM-1 and B7-2 surface expression, impairing B cell induction of T cell activation.