Genome Biology

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Complex genetic diseases: controversy over the Croesus code

Alan F Wright* and Nicholas D Hastie

Genome Biology 2001, 2:comment2007-comment2007.8 doi:10.1186/gb-2001-2-8-comment2007

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What is complex about complex disorders?

Kevin J Mitchell Genome Biology 2012, 13:237 (23 January 2012)

Complex disorders such as diabetes and schizophrenia are really groups of many distinct genetic disorders caused by rare, recent deleterious mutations

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New methods for finding disease-susceptibility genes: impact and potential

Mark I McCarthy, Damian Smedley, Winston Hide Genome Biology 2003, 4:119 (19 September 2003)

Improved techniques for defining disease-gene location and evaluating the biological candidacy of regional transcripts will hasten disease-gene discovery.