Complex genetic diseases: controversy over the Croesus code
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* Corresponding author: Alan F Wright alan.wright@hgu.mrc.ed.ac.uk
Genome Biology 2001, 2:comment2007-comment2007.8 doi:10.1186/gb-2001-2-8-comment2007
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What is complex about complex disorders? Kevin J Mitchell Genome Biology 2012, 13:237 (23 January 2012) Complex disorders such as diabetes and schizophrenia are really groups of many distinct genetic disorders caused by rare, recent deleterious mutations
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New methods for finding disease-susceptibility genes: impact and potential Mark I McCarthy, Damian Smedley, Winston Hide Genome Biology 2003, 4:119 (19 September 2003) Improved techniques for defining disease-gene location and evaluating the biological candidacy of regional transcripts will hasten disease-gene discovery. |