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AFM 4.0: a toolbox for DNA microarray analysis

Bobby-Joe Breitkreutz1, Paul Jorgensen12, Ashton Breitkreutz12 and Mike Tyers12*

Author Affiliations

1 Programme in Molecular Biology and Cancer, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Canada, M5G 1X5

2 Graduate Department of Medical Genetics and Microbiology, University of Toronto, Toronto, Canada, M5S 1A8

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Genome Biology 2001, 2:software0001-software0001.3  doi:10.1186/gb-2001-2-8-software0001


Disclaimer: Whilst every effort is made by the authors, editors and publishers to ensure that the software performs as described, they accept no liability whatsoever for the consequences of downloading or using it. This information has not been peer-reviewed. Responsibility rests solely with the author(s).

Published: 6 August 2001

Abstract

We have developed a series of programs, collectively packaged as Array File Maker 4.0 (AFM), that manipulate and manage DNA microarray data. AFM 4.0 is simple to use, applicable to any organism or microarray, and operates within the familiar confines of Microsoft Excel. Given a database of expression ratios, AFM 4.0 generates input files for clustering, helps prepare colored figures and Venn diagrams, and can uncover aneuploidy in yeast microarray data. AFM 4.0 should be especially useful to laboratories that do not have access to specialized commercial or in-house software.