Figure 2.

Distribution of hexamer dissimilarity test results from pure and mixed-culture libraries. (a) Calculation of statistical parameters from cdfs A and B. Overlap in the upper tail of cdfA with cdfB and the lower tail of cdfB with cdfA are likely regions for error. We find the false-positive rate α where 1 - cdfA intersects 0 [cdfA(0)= 1 - α], and the false-negative rate β where cdfB crosses 0. Also shown are the medians (μ) for each distribution, where cdf(μ) = 0.5. (b) Calibration curves for plant (A1, Glycine and Medicago spp., solid black line) and stramenopile plus P. infestans EST (B1, dashed black line) training sequences. Superimposed distributions of test results show dissimilarity differences for infected G. max (green) and axenic P. sojae mycelial and zoospore sequences (blue and cyan, respectively).

Hraber and Weller Genome Biology 2001 2:research0037.1   doi:10.1186/gb-2001-2-9-research0037