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Highly AccessReview

The nuclear pore complex

Stephen A Adam email

Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA

author email corresponding author email

Genome Biology 2001, 2:reviews0007.1-0007.6doi:10.1186/gb-2001-2-9-reviews0007

Published: 31 August 2001

Subject areas: Cell biology, Biochemistry and structural biology, Evolution

Abstract

Nuclear pore complexes, the conduits for information exchange between the nucleus and cytoplasm, appear broadly similar in eukaryotes from yeast to human. Precisely how nuclear pore complexes regulate macromolecular and ionic traffic remains unknown, but recent advances in the identification and characterization of components of the complex by proteomics and genomics have provided new insights.


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