The nuclear pore complex
Department of Cell and Molecular Biology, Northwestern University Medical School, Chicago, IL 60611, USA
Genome Biology 2001, 2:reviews0007-reviews0007.6 doi:10.1186/gb-2001-2-9-reviews0007Published: 31 August 2001
Nuclear pore complexes, the conduits for information exchange between the nucleus and cytoplasm, appear broadly similar in eukaryotes from yeast to human. Precisely how nuclear pore complexes regulate macromolecular and ionic traffic remains unknown, but recent advances in the identification and characterization of components of the complex by proteomics and genomics have provided new insights.