Genome Biology

official impact factor 6.89

Review

Dating branches on the Tree of Life using DNA

Gregory A Wray

Author Affiliations

Department of Biology, Duke University, Durham, NC 27708-0338, USA

Genome Biology 2001, 3:reviews0001-reviews0001.7 doi:10.1186/gb-2001-3-1-reviews0001

Published: 20 December 2001

Abstract

The use of DNA sequences to estimate the timing of evolutionary events is increasingly popular, although it is fraught with practical difficulties. But the exponential growth of relevant information and improved methods of analysis are providing increasingly reliable sequence-derived dates, and it may become possible to reconcile fossil-derived and molecular estimates of divergence times within the next few years.