Table 1 |
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A summary of the three branches of the complement activation pathway |
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| Classical pathway |
Lectin pathway |
Alternative pathway |
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| Triggering factor |
Antigen-antibody complexes |
Mannan-binding lectin |
Pathogen (directly) |
| Proteases involved |
C1r, C1s and C2 |
MASP-1, MASP-2 and MASP-3 |
Factor D and Factor B |
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Nonaka and Miyazawa Genome Biology 2001 3:reviews1001.1 doi:10.1186/gb-2001-3-1-reviews1001 |
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