Email updates

Keep up to date with the latest news and content from Genome Biology and BioMed Central.

Paper report

Autosome inactivation by ectopic XIST in differentiated cells

Cathy Holding

  • Correspondence: Cathy Holding

Author Affiliations

Genome Biology 2002, 3:reports0053  doi:10.1186/gb-2002-3-10-reports0053

Published: 30 September 2002

Abstract

Human XIST, when integrated into autosomes in a fully differentiated adult human tumor cell line, caused localized chromosome inactivation, counter to all previous concepts of a specific narrow window of opportunity for X-inactivation