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A genomic approach to studying cell-size homeostasis in yeast

Jonathan BA Millar

Author Affiliations

Division of Yeast Genetics, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK

Genome Biology 2002, 3:reviews1028-reviews1028.4  doi:10.1186/gb-2002-3-10-reviews1028

Published: 20 September 2002

Abstract

Using a complete set of budding-yeast mutants bearing deletions of all known open reading frames, a recent study has revealed multiple overlapping pathways that coordinately regulate cell-cycle progression with ribosome biogenesis and translation efficiency, providing new insights into the mechanisms governing cell-size homeostasis in eukaryotes.