Figure 4.
Fuzzy clustering of yeast genomic expression data. (a) Each row in this diagram represents one of the 91 centroids identified by fuzzy k-means
clustering. The data representation is the same as described in Figure 1. (b) Genes were assigned to each of the centroids shown in (a) using a membership cutoff
of 0.08, as described in the text. Each cluster of selected genes is separated by
a horizontal gray line. Examples of functionally related clusters of genes are indicated
by numbers to the right of (b): cluster 2, amino-acid biosynthesis genes; cluster
7, genes induced as part of the environmental stress response; cluster 14, mitochondrial
protein synthesis genes; cluster 39, genes involved in nitrogen utilization; cluster
45, oxidative phosphorylation and respiration components; cluster 53, specific amino-acid
transporters; cluster 67, glycolysis genes; cluster 68, proteasome components; cluster
72, secretion, protein synthesis, and membrane synthesis genes; cluster 73, genes
repressed as part of the environmental stress response; cluster 80, aminoacid biosynthesis
genes; cluster 82, G2/M cyclins; cluster 86, histone genes. The complete clustering
results can be viewed at [14].
Gasch and Eisen Genome Biology 2002 3:research0059.1 doi:10.1186/gb-2002-3-11-research0059 |