Table 1

Useful databases for identifying alternatively spliced RNAs and regulatory elementsof alternative splicing data

Name
Description
URL
Published reference

Alternative Splicing database
Alternative exon database compiled from the literature
http://cgsigma.cshl.org/new_alt_exon_db2/ webcite
[40]
Alternative splicing databases
Several alternative splicing databases, including a database of splice variants of disease genes, a complete splice-site database, and a database of alternative splice forms for seven organisms
http://www.bioinf.mdc-berlin.de/splice/ webcite

AltExtron
Transcript-confirmed human introns and exons; includes alternatively spliced data subsets
http://www.bit.uq.edu.au/altExtron/ webcite or http://www.ebi.ac.uk/~thanaraj/altExtron/ webcite
[6]
ASAP
Human alternative splicing database; part of the Alternative Splicing Annotation Project
http://www.bioinformatics.ucla.edu/HASDB webcite
[43]
ASDB
Alternatively spliced gene database; includes protein and nucleotide sequences for human, mouse, rat, Drosophila, Caenorhabditis elegans, chicken, cow and rabbit and viruses
http://cbcg.nersc.gov/asdb webcite
[41]
AsMamDB
Alternatively spliced mammalian genes; includes human, mouse, and rat
http://166.111.30.65/ASMAMDB.html webcite
[42]
Gene Resource Locator
Gene map database; includes information on alternatively spliced transcripts
http://grl.gi.k.u-tokyo.ac.jp webcite
[44]
Intronerator
Introns in C. elegans; includes a catalog of alternatively spliced transcripts
http://www.cse.ucsc.edu/~kent/intronerator/ webcite
[45]
ISIS
All introns identified in GenBank
http://isis.bit.uq.edu.au/ webcite
[46]
PALS db
Putative alternative splicing predicted by EST alignments for mouse and human
http://palsdb.ym.edu.tw/ webcite
[47]
SELEX-DB
In vitro selected oligomers; includes SELEX sequences for splicing factors and is supplemented by SYSTEM (experimental design) and CROSS_TEST (cross-validation test) databases
http://wwwmgs.bionet.nsc.ru/mgs/systems/selex/ webcite
[48]
SpliceDB
Mammalian splice sites
http://genomic.sanger.ac.uk/spldb/SpliceDB.html webcite or http://www.softberry.com/spldb/SpliceDB.html webcite
[49]
SpliceNest
A database that maps GeneNest onto human genomic sequence and is integrated with GeneNest (EST clusters for human, mouse, zebrafish and Arabidopsis thaliana) and SYSTERS (protein sequence clusters) databases
http://splicenest.molgen.mpg.de/ webcite
[50]
STACK
Putative human transcripts reconstructed from ESTs; includes the context of different tissues or pathological states
http://www.sanbi.ac.za/Dbases.html webcite
[51]
Yeast Intron Database
Introns in Saccharomyces cerevisiae
http://www.cse.ucsc.edu/research/compbio/yeast_introns.html webcite
[52]

Ladd and Cooper Genome Biology 2002 3:reviews0008.1   doi:10.1186/gb-2002-3-11-reviews0008