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The discovery of novel neuropeptides takes flight

Ruthann Nichols email

Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109-0606, USA

author email corresponding author email

Genome Biology 2002, 3:reviews1032.1-1032.2doi:10.1186/gb-2002-3-11-reviews1032

Published: 28 October 2002

Subject areas: Neurobiology, Biochemistry and structural biology, Genome studies

Abstract

Structural data are critical for the elucidation of how peptides are synthesized and how they function. Two recent studies have used nanoscale chromatography together with mass spectrometry to determine the structures of novel neuropeptides in rat and Drosophila. The results shed light on neuropeptide synthesis and function(s) in both vertebrates and insects.


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