Plasmodium falciparum virulence determinants unveiled
The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria 3050, Australia
Genome Biology 2002, 3:reviews1031-reviews1031.4 doi:10.1186/gb-2002-3-11-reviews1031Published: 25 October 2002
The human malaria parasite Plasmodium falciparum, one of the world's most devastating pathogens, has an astonishing array of sequences and genes that play key roles in pathogenesis and immune evasion. We must understand the functions of these elements if the chronicity and unpredictable virulence of Plasmodium is to be explained.