Table 3

Phenotypes for which QTLs have been generated using strains that have whole genome draft sequence available


Phenotype
Number of QTLs (B6xD2)

1
Alcohol drinking - preference
7
2
Alcohol drinking - acceptance
1
3
Alcohol conditioned taste aversion
3
4
Cocaine seizures
3
5
Morphine preference
1
6
Morphine analgesia
2
7
Screen test sensitivity
8
8
Ethanol-induced locomotor activity
3
9
Basal activity
1
11
Acute alcohol withdrawal
5
12
Acute pentobarbital withdrawal
3
13
Chronic alcohol withdrawal
3
14
LORR duration
4*
15
LORR Bec
14*
16
Free-choice ethanol consumption
6*
17
Behavioral effect of stress
7*
18
Porphyria
3
19
Liver injury and porphyria
3
20
Lymphocyte proportion B220 (%)
2
21
Lymphocyte proportion CD4 (%)
1
22
Lymphocyte proportion CD8 (%)
1
23
Hepatic lipid peroxidation potential
1
24
Peak bone mass
16*
25
Variation in TRBV4 expansion
2
26
Maximal electroshock seizure threshold
4
27
Variation in cerebellar size
4
28
Variation in IGL volume
1
29
Susceptibility to mycobacterium tuberculosis
2, 1
30
Acute behavioral sensitivity to paraoxon
6*
31
Circadian period of locomotor activity
1
32
Short-term intake of saccharin
1
33
Short-term intake of sucrose
1
34
Short-term intake of quinine
1
35
Testicular weight
1
36
Bone density
6
37
Contextual fear conditioning
5
38
Hypothermic sensitivity to quinpirole
1
39
Tolerance to quinpirole
1
40
Sensitivity and tolerance to quinpirole-induced hypothermia
1
41
Baseline locomoter activity
3
42
Locomotor sensitivity to quinpirole
1
43
Hypnotic sensitivity to ethanol
1*, 1
44
Body weight
1
45
Tail length
1
46
Methamphetamine responses


     Chewing
5

     Climbing
14

     Home cage locomotor activity
20

     Body temperature change
22
47
Pcp-induced behavior
3*
48
Amp-induced behavior
6*
49
Antinociceptive responsiveness to N2O
7
50
Corticosterone response to ethanol
5
51
High-affinity choline uptake
1

Phenotype
Number of QTLs (B6xA/J)

52
Cocaine-induced locomotor activity
2
53
Seizure susceptibility (beta-CCM administration)
3
54
Habituated open field behavior
2, 5
55
Hormone-induced ovulation rate
2, 5
56
Light-to-dark transition behavior
3, 5
57
Center time behavior
5
58
Initial ambulation in the open field
1, 4
59
Vertical rearings
1, 2
60
Trypanosomosis resistance
1
61
Nickel-induced acute lung injury
1, 2
62
PKC-alpha content
1
63
PKC activity
1

Total number of QTLs
276

*QTLs identified as suggestive in the original publications. QTLs identified as provisional in the original publications.

Marshall et al. Genome Biology 2002 3:research0078.1   doi:10.1186/gb-2002-3-12-research0078