|
Phenotypes for which QTLs have been generated using strains that have whole genome draft sequence available |
||
| Phenotype |
Number of QTLs (B6xD2) |
|
|
|
||
| 1 |
Alcohol drinking - preference |
7 |
| 2 |
Alcohol drinking - acceptance |
1 |
| 3 |
Alcohol conditioned taste aversion |
3 |
| 4 |
Cocaine seizures |
3 |
| 5 |
Morphine preference |
1 |
| 6 |
Morphine analgesia |
2 |
| 7 |
Screen test sensitivity |
8 |
| 8 |
Ethanol-induced locomotor activity |
3 |
| 9 |
Basal activity |
1 |
| 11 |
Acute alcohol withdrawal |
5 |
| 12 |
Acute pentobarbital withdrawal |
3 |
| 13 |
Chronic alcohol withdrawal |
3 |
| 14 |
LORR duration |
4* |
| 15 |
LORR Bec |
14* |
| 16 |
Free-choice ethanol consumption |
6* |
| 17 |
Behavioral effect of stress |
7* |
| 18 |
Porphyria |
3 |
| 19 |
Liver injury and porphyria |
3 |
| 20 |
Lymphocyte proportion B220 (%) |
2 |
| 21 |
Lymphocyte proportion CD4 (%) |
1† |
| 22 |
Lymphocyte proportion CD8 (%) |
1 |
| 23 |
Hepatic lipid peroxidation potential |
1 |
| 24 |
Peak bone mass |
16* |
| 25 |
Variation in TRBV4 expansion |
2 |
| 26 |
Maximal electroshock seizure threshold |
4 |
| 27 |
Variation in cerebellar size |
4 |
| 28 |
Variation in IGL volume |
1 |
| 29 |
Susceptibility to mycobacterium tuberculosis |
2, 1† |
| 30 |
Acute behavioral sensitivity to paraoxon |
6* |
| 31 |
Circadian period of locomotor activity |
1† |
| 32 |
Short-term intake of saccharin |
1 |
| 33 |
Short-term intake of sucrose |
1 |
| 34 |
Short-term intake of quinine |
1 |
| 35 |
Testicular weight |
1 |
| 36 |
Bone density |
6 |
| 37 |
Contextual fear conditioning |
5 |
| 38 |
Hypothermic sensitivity to quinpirole |
1 |
| 39 |
Tolerance to quinpirole |
1† |
| 40 |
Sensitivity and tolerance to quinpirole-induced hypothermia |
1† |
| 41 |
Baseline locomoter activity |
3† |
| 42 |
Locomotor sensitivity to quinpirole |
1† |
| 43 |
Hypnotic sensitivity to ethanol |
1*, 1† |
| 44 |
Body weight |
1 |
| 45 |
Tail length |
1 |
| 46 |
Methamphetamine responses |
|
| Chewing |
5 |
|
| Climbing |
14 |
|
| Home cage locomotor activity |
20 |
|
| Body temperature change |
22 |
|
| 47 |
Pcp-induced behavior |
3* |
| 48 |
Amp-induced behavior |
6* |
| 49 |
Antinociceptive responsiveness to N2O |
7 |
| 50 |
Corticosterone response to ethanol |
5 |
| 51 |
High-affinity choline uptake |
1† |
| Phenotype |
Number of QTLs (B6xA/J) |
|
|
|
||
| 52 |
Cocaine-induced locomotor activity |
2 |
| 53 |
Seizure susceptibility (beta-CCM administration) |
3 |
| 54 |
Habituated open field behavior |
2, 5† |
| 55 |
Hormone-induced ovulation rate |
2, 5† |
| 56 |
Light-to-dark transition behavior |
3, 5† |
| 57 |
Center time behavior |
5† |
| 58 |
Initial ambulation in the open field |
1, 4† |
| 59 |
Vertical rearings |
1, 2† |
| 60 |
Trypanosomosis resistance |
1 |
| 61 |
Nickel-induced acute lung injury |
1, 2† |
| 62 |
PKC-alpha content |
1 |
| 63 |
PKC activity |
1 |
| Total number of QTLs |
276 |
|
|
*QTLs identified as suggestive in the original publications. †QTLs identified as provisional in the original publications. | ||
Marshall et al. Genome Biology 2002 3:research0078.1 doi:10.1186/gb-2002-3-12-research0078 |
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