Genome Biology
Volume 3
Issue 12 |
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MinireviewRNAi hushes heterochromatinJulie M Bailis and Susan L Forsburg  Molecular and Cellular Biology Laboratory, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA  author email corresponding author email
Genome Biology 2002,
3:reviews1035.1-1035.4doi:10.1186/gb-2002-3-12-reviews1035
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28 November 2002 |
Subject areas: Molecular biology, Cell biology, Genetics Abstract
Repeated DNA elements and region-specific protein modifications combine within chromosomes to form a transcriptionally silent chromatin structure called heterochromatin. Recent work in the fission yeast Schizosaccharomyces pombe reveals that RNA is also an integral component of silent heterochromatin, providing a new perspective on how heterochromatin is organized and maintained in eukaryotic cells. | 
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