Vanaso and α-Spec are separate annotations that share an untranslated 5' exon. Only evidence (black panel) directly used to annotate the gene models (cyan panel) is shown. Coding sequences are delineated by green vertical lines (starts of translation) and red vertical lines (stops of translation). The Release 3 annotations Vanaso and α-Spec (dark blue) on chromosome arm 3L overlap at their most distal 5' end, sharing a portion of their untranslated regions. These gene models are supported by many ESTs and cDNA sequencing reads (light green), a complete cDNA clone (dark green), and several GenBank records (dark green). In spite of the shared initiation point for these transcripts, none of the remaining exons or coding sequences coincides. Note the small exon (arrow) predicted by Genie and GENSCAN. This exon is not included in the α-Spec annotation, for lack of other supporting evidence, but alternative cDNA clones including this exon will be screened for directly in cDNA libraries .
Misra et al. Genome Biology 2002 3:research0083.1-0083.22 doi:10.1186/gb-2002-3-12-research0083